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MOBILE GENOMES

'We investigate the patterns and mechanisms of genomic variation in disease'

Paula Otero, PhD

paulaotero.sanchez@.usc.es

Some years ago, I earned a BSc in Biomedical Science at the University of Lleida, where I first became interested in genetics. Back in Galicia, I pursued that passion by completing an MSc in Genomics and Genetics. During my PhD, I worked on a project investigating the role of the hepatitis B virus in the origins of liver cancer—a project I continue to pursue today. In my free time, I enjoy reading, swimming, and eating popcorn, but above all, I’m a huge Formula 1 fan.


Education, Grants and Awards


Publications

  1. Álvarez, E.G., Demeulemeester, J.#, Otero, P.#, Jolly, C.#, García-Souto, D.#, et al. Aberrant integration of hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture. 2021, Nature Communications, (12) 6910. (#equal contribution)
  2. Álvarez, E.G.#, Otero, P.#, Rodríguez-Martín, B., Pequeño-Valtierra, A., Otero, I., et al.Characterization of Human Herpesvirus 8 genomic integration and amplification events in a primary effusion lymphoma cell line. 2023, Frontiers in Virology, 3. (#equal contribution)
  3. Zumalave, S., Santamarina, M., Espasandín, N.P., García-Souto, D., Temes, J., et al. Synchronous L1 retrotransposition events promote chromosomal crossover early in human tumorigenesis. 2024, bioRxiv. (Includes Otero, P.)


Dissemination activities

CiMUS Podcast

Ciencia e Tal